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Saturation scanning of ubiquitin variants reveals a common hot spot for binding to USP2 and USP21
A detailed understanding of the molecular mechanisms whereby ubiquitin (Ub) recognizes enzymes in the Ub proteasome system is crucial for understanding the biological function of Ub. Many structures of Ub complexes have been solved and, in most cases, reveal a large structural epitope on a common fa...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978272/ https://ncbi.nlm.nih.gov/pubmed/27436899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524648113 |
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