HIF2α–arginase axis is essential for the development of pulmonary hypertension

Hypoxic pulmonary vasoconstriction is correlated with pulmonary vascular remodeling. The hypoxia-inducible transcription factors (HIFs) HIF-1α and HIF-2α are known to contribute to the process of hypoxic pulmonary vascular remodeling; however, the specific role of pulmonary endothelial HIF expressio...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Cowburn, Andrew S., Crosby, Alexi, Macias, David, Branco, Cristina, Colaço, Renato D. D. R., Southwood, Mark, Toshner, Mark, Crotty Alexander, Laura E., Morrell, Nicholas W., Chilvers, Edwin R., Johnson, Randall S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978263/
https://ncbi.nlm.nih.gov/pubmed/27432976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602978113
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares