HIF2α–arginase axis is essential for the development of pulmonary hypertension

Hypoxic pulmonary vasoconstriction is correlated with pulmonary vascular remodeling. The hypoxia-inducible transcription factors (HIFs) HIF-1α and HIF-2α are known to contribute to the process of hypoxic pulmonary vascular remodeling; however, the specific role of pulmonary endothelial HIF expressio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Cowburn, Andrew S., Crosby, Alexi, Macias, David, Branco, Cristina, Colaço, Renato D. D. R., Southwood, Mark, Toshner, Mark, Crotty Alexander, Laura E., Morrell, Nicholas W., Chilvers, Edwin R., Johnson, Randall S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978263/
https://ncbi.nlm.nih.gov/pubmed/27432976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602978113
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