Transcription Factor Hepatocyte Nuclear Factor–1β Regulates Renal Cholesterol Metabolism

HNF-1β is a tissue–specific transcription factor that is expressed in the kidney and other epithelial organs. Humans with mutations in HNF-1β develop kidney cysts, and HNF-1β regulates the transcription of several cystic disease genes. However, the complete spectrum of HNF-1β–regulated genes and pat...

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Dettagli Bibliografici
Pubblicato in:J Am Soc Nephrol
Autori principali: Aboudehen, Karam, Kim, Min Soo, Mitsche, Matthew, Garland, Kristina, Anderson, Norma, Noureddine, Lama, Pontoglio, Marco, Patel, Vishal, Xie, Yang, DeBose-Boyd, Russell, Igarashi, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2016
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978044/
https://ncbi.nlm.nih.gov/pubmed/26712526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015060607
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