Induction of endonuclease-mediated apoptosis in tumor cells by C-nitroso-substituted ligands of poly(ADP-ribose) polymerase.

6-Nitroso-1,2-benzopyrone and 3-nitrosobenzamide, two C-nitroso compounds that inactivate the eukaryotic nuclear protein poly(ADP-ribose) polymerase [NAD+:poly(adenosine diphosphate D-ribose) ADP-D-ribosyltransferase, ADPRT, EC 2.4.2.30] at one zinc-finger site, completely suppressed the proliferati...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Rice, W G, Hillyer, C D, Harten, B, Schaeffer, C A, Dorminy, M, Lackey, D A, Kirsten, E, Mendeleyev, J, Buki, K G, Hakam, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49779/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502187/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7703
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