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Efficacy and safety of Dexrazoxane (DRZ) in sarcoma patients receiving high cumulative doses of anthracycline therapy – a retrospective study including 32 patients

BACKGROUND: Anthracyclines, as the most effective therapy, are the cornerstone of advanced stage sarcoma treatment. However, anthracyclines can also contribute to myocardial dysfunction and congestive heart failure, ultimately limiting the therapeutic potential of the drug. Coadministration of Dexra...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Schuler, Markus K., Gerdes, Sebastian, West, Antje, Richter, Stephan, Busemann, Christoph, Hentschel, Leopold, Lenz, Felicitas, Kopp, Hans-Georg, Ehninger, Gerhard, Reichardt, Peter, Pink, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977890/
https://ncbi.nlm.nih.gov/pubmed/27507014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2654-x
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