Efficacy and safety of Dexrazoxane (DRZ) in sarcoma patients receiving high cumulative doses of anthracycline therapy – a retrospective study including 32 patients

BACKGROUND: Anthracyclines, as the most effective therapy, are the cornerstone of advanced stage sarcoma treatment. However, anthracyclines can also contribute to myocardial dysfunction and congestive heart failure, ultimately limiting the therapeutic potential of the drug. Coadministration of Dexra...

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Publicat a:BMC Cancer
Autors principals: Schuler, Markus K., Gerdes, Sebastian, West, Antje, Richter, Stephan, Busemann, Christoph, Hentschel, Leopold, Lenz, Felicitas, Kopp, Hans-Georg, Ehninger, Gerhard, Reichardt, Peter, Pink, Daniel
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977890/
https://ncbi.nlm.nih.gov/pubmed/27507014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2654-x
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