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uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R

BACKGROUND: Due to lack of a targeted therapy for the triple-negative breast cancer (TNBC) patients, it is important to explore this aggressive breast cancer type in more detail and to establish novel therapeutic approaches. TNBC is defined negative for the protein expression of oestrogen receptor (...

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Detalles Bibliográficos
Publicado en:BMC Cancer
Main Authors: Huber, Michaela C., Mall, Rebecca, Braselmann, Herbert, Feuchtinger, Annette, Molatore, Sara, Lindner, Katrin, Walch, Axel, Gross, Eva, Schmitt, Manfred, Falkenberg, Natalie, Aubele, Michaela
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977758/
https://ncbi.nlm.nih.gov/pubmed/27502396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2663-9
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