uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R

BACKGROUND: Due to lack of a targeted therapy for the triple-negative breast cancer (TNBC) patients, it is important to explore this aggressive breast cancer type in more detail and to establish novel therapeutic approaches. TNBC is defined negative for the protein expression of oestrogen receptor (...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Huber, Michaela C., Mall, Rebecca, Braselmann, Herbert, Feuchtinger, Annette, Molatore, Sara, Lindner, Katrin, Walch, Axel, Gross, Eva, Schmitt, Manfred, Falkenberg, Natalie, Aubele, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977758/
https://ncbi.nlm.nih.gov/pubmed/27502396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2663-9
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