uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R

BACKGROUND: Due to lack of a targeted therapy for the triple-negative breast cancer (TNBC) patients, it is important to explore this aggressive breast cancer type in more detail and to establish novel therapeutic approaches. TNBC is defined negative for the protein expression of oestrogen receptor (...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Huber, Michaela C., Mall, Rebecca, Braselmann, Herbert, Feuchtinger, Annette, Molatore, Sara, Lindner, Katrin, Walch, Axel, Gross, Eva, Schmitt, Manfred, Falkenberg, Natalie, Aubele, Michaela
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977758/
https://ncbi.nlm.nih.gov/pubmed/27502396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2663-9
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