The highly expressed 5’isomiR of hsa-miR-140-3p contributes to the tumor-suppressive effects of miR-140 by reducing breast cancer proliferation and migration

BACKGROUND: miRNAs are small noncoding RNA molecules that play an important role in post-transcriptional regulation of gene expression. Length and/or sequence variants of the same miRNA are termed isomiRs. While most isomiRs are functionally redundant compared to their canonical counterparts, the so...

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Publicat a:BMC Genomics
Autors principals: Salem, Omar, Erdem, Nese, Jung, Janine, Münstermann, Ewald, Wörner, Angelika, Wilhelm, Heike, Wiemann, Stefan, Körner, Cindy
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977694/
https://ncbi.nlm.nih.gov/pubmed/27502506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2869-x
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