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Investigating the potential role of non-vls genes on linear plasmid 28–1 in virulence and persistence by Borrelia burgdorferi

BACKGROUND: The lp28-1 plasmid is required for persistent infection by the Lyme disease spirochete, Borrelia burgdorferi. Mutational studies on this plasmid have shown that the vls locus is important for antigenic variation of the VlsE lipoprotein that leads to immune evasion and persistence. Howeve...

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Detalles Bibliográficos
Publicado en:BMC Microbiol
Main Authors: Magunda, Petronella R. Hove, Bankhead, Troy
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977671/
https://ncbi.nlm.nih.gov/pubmed/27502325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0806-4
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