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Investigating the potential role of non-vls genes on linear plasmid 28–1 in virulence and persistence by Borrelia burgdorferi

BACKGROUND: The lp28-1 plasmid is required for persistent infection by the Lyme disease spirochete, Borrelia burgdorferi. Mutational studies on this plasmid have shown that the vls locus is important for antigenic variation of the VlsE lipoprotein that leads to immune evasion and persistence. Howeve...

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Pubblicato in:BMC Microbiol
Autori principali: Magunda, Petronella R. Hove, Bankhead, Troy
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977671/
https://ncbi.nlm.nih.gov/pubmed/27502325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0806-4
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