The mRNA capping enzyme of Saccharomyces cerevisiae has dual specificity to interact with CTD of RNA Polymerase II

RNA Polymerase II (RNAPII) uniquely possesses an extended carboxy terminal domain (CTD) on its largest subunit, Rpb1, comprising a repetitive Tyr(1)Ser(2)Pro(3)Thr(4) Ser(5)Pro(6)Ser(7) motif with potential phosphorylation sites. The phosphorylation of the CTD serves as a signal for the binding of v...

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Udgivet i:Sci Rep
Main Authors: Bharati, Akhilendra Pratap, Singh, Neha, Kumar, Vikash, Kashif, Md., Singh, Amit Kumar, Singh, Priyanka, Singh, Sudhir Kumar, Siddiqi, Mohammad Imran, Tripathi, Timir, Akhtar, Md. Sohail
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977518/
https://ncbi.nlm.nih.gov/pubmed/27503426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31294
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