ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae.

Saccharomyces cerevisiae translation initiation factor eIF-4A, an RNA helicase of the Asp-Glu-Ala-Asp (DEAD) box protein family, was mutated in the putative ATP binding site and expressed in Escherichia coli. Mutant proteins with alanine at position 66 replaced by glycine [eIF-4A(A66G)] or valine [e...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Blum, S, Schmid, S R, Pause, A, Buser, P, Linder, P, Sonenberg, N, Trachsel, H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502180/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7664
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