The Genomic Scrapheap Challenge; Extracting Relevant Data from Unmapped Whole Genome Sequencing Reads, Including Strain Specific Genomic Segments, in Rats

Unmapped next-generation sequencing reads are typically ignored while they contain biologically relevant information. We systematically analyzed unmapped reads from whole genome sequencing of 33 inbred rat strains. High quality reads were selected and enriched for biologically relevant sequences; si...

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Udgivet i:PLoS One
Main Authors: van der Weide, Robin H., Simonis, Marieke, Hermsen, Roel, Toonen, Pim, Cuppen, Edwin, de Ligt, Joep
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976967/
https://ncbi.nlm.nih.gov/pubmed/27501045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160036
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