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NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption

BACKGROUND: NH125, a known WalK inhibitor kills MRSA persisters. However, its precise mode of action is still unknown. METHODS & RESULTS: The mode of action of NH125 was investigated by comparing its spectrum of antimicrobial activity and its effects on membrane permeability and giant unilamella...

詳細記述

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書誌詳細
出版年:Future Med Chem
主要な著者: Kim, Wooseong, Fricke, Nico, Conery, Annie L, Fuchs, Beth Burgwyn, Rajamuthiah, Rajmohan, Jayamani, Elamparithi, Vlahovska, Petia M, Ausubel, Frederick M, Mylonakis, Eleftherios
フォーマット: Artigo
言語:Inglês
出版事項: Future Science Ltd 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976882/
https://ncbi.nlm.nih.gov/pubmed/26910612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.15.189
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