Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening

AIM: To determine whether single nucleotide polymorphisms (SNPs) can be used to identify people who should be screened for colorectal cancer. METHODS: We simulated one million people with and without colorectal cancer based on published SNP allele frequencies and strengths of colorectal cancer assoc...

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Vydáno v:Future Oncol
Hlavní autoři: Jenkins, Mark A, Makalic, Enes, Dowty, James G, Schmidt, Daniel F, Dite, Gillian S, MacInnis, Robert J, Ait Ouakrim, Driss, Clendenning, Mark, Flander, Louisa B, Stanesby, Oliver K, Hopper, John L, Win, Aung K, Buchanan, Daniel D
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976832/
https://ncbi.nlm.nih.gov/pubmed/26846999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.15.303
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