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Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening

AIM: To determine whether single nucleotide polymorphisms (SNPs) can be used to identify people who should be screened for colorectal cancer. METHODS: We simulated one million people with and without colorectal cancer based on published SNP allele frequencies and strengths of colorectal cancer assoc...

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Bibliografiske detaljer
Udgivet i:Future Oncol
Main Authors: Jenkins, Mark A, Makalic, Enes, Dowty, James G, Schmidt, Daniel F, Dite, Gillian S, MacInnis, Robert J, Ait Ouakrim, Driss, Clendenning, Mark, Flander, Louisa B, Stanesby, Oliver K, Hopper, John L, Win, Aung K, Buchanan, Daniel D
Format: Artigo
Sprog:Inglês
Udgivet: Future Medicine Ltd 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976832/
https://ncbi.nlm.nih.gov/pubmed/26846999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.15.303
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