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Recombinant human interleukin-1 receptor antagonist promotes M1 microglia biased cytokines and chemokines following human traumatic brain injury

Interleukin-1 receptor antagonist (IL1ra) has demonstrated efficacy in a wide range of animal models of neuronal injury. We have previously published a randomised controlled study of IL1ra in human severe TBI, with concomitant microdialysis and plasma sampling of 42 cytokines and chemokines. In this...

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Bibliografiska uppgifter
I publikationen:J Cereb Blood Flow Metab
Huvudupphovsmän: Helmy, Adel, Guilfoyle, Mathew R, Carpenter, Keri LH, Pickard, John D, Menon, David K, Hutchinson, Peter J
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publications 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976751/
https://ncbi.nlm.nih.gov/pubmed/26661249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15620204
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