Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial

Traumatic brain injury (TBI) is the commonest cause of death and disability in those aged under 40 years. Interleukin-1 receptor antagonist (IL1ra) is an endogenous competitive antagonist at the interleukin-1 type-1 receptor (IL-1R). Antagonism at the IL-1R confers neuroprotection in several rodent...

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Bibliographische Detailangaben
Hauptverfasser: Helmy, Adel, Guilfoyle, Mathew R, Carpenter, Keri LH, Pickard, John D, Menon, David K, Hutchinson, Peter J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013762/
https://ncbi.nlm.nih.gov/pubmed/24569690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.23
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