PI3Kα and STAT1 Interplay Regulates Human Mesenchymal Stem Cell Immune Polarization

The immunomodulatory capacity of mesenchymal stem cells (MSCs) is critical for their use in therapeutic applications. MSC response to specific inflammatory cues allows them to switch between a proinflammatory (MSC1) or anti-inflammatory (MSC2) phenotype. Regulatory mechanisms controlling this switch...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Mounayar, Marwan, Kefaloyianni, Eirini, Smith, Brian, Solhjou, Zhabiz, Maarouf, Omar H., Azzi, Jamil, Chabtini, Lola, Fiorina, Paolo, Kraus, Morey, Briddell, Robert, Fodor, William, Herrlich, Andreas, Abdi, Reza
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976699/
https://ncbi.nlm.nih.gov/pubmed/25753288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1986
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