PI3Kα and STAT1 Interplay Regulates Human Mesenchymal Stem Cell Immune Polarization

The immunomodulatory capacity of mesenchymal stem cells (MSCs) is critical for their use in therapeutic applications. MSC response to specific inflammatory cues allows them to switch between a proinflammatory (MSC1) or anti-inflammatory (MSC2) phenotype. Regulatory mechanisms controlling this switch...

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Udgivet i:Stem Cells
Main Authors: Mounayar, Marwan, Kefaloyianni, Eirini, Smith, Brian, Solhjou, Zhabiz, Maarouf, Omar H., Azzi, Jamil, Chabtini, Lola, Fiorina, Paolo, Kraus, Morey, Briddell, Robert, Fodor, William, Herrlich, Andreas, Abdi, Reza
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976699/
https://ncbi.nlm.nih.gov/pubmed/25753288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1986
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