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Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells.

Gene transfer into hemopoietic stem cells could offer a lasting cure for a variety of congenital disorders. As a preclinical test for such a gene therapy, rhesus monkeys were transplanted with autologous bone-marrow cells infected with helper-free recombinant retroviruses carrying the human adenosin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van Beusechem, V W, Kukler, A, Heidt, P J, Valerio, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49766/
https://ncbi.nlm.nih.gov/pubmed/1502175
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