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N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3

The balance between neutrophil serine proteases (NSPs) and protease inhibitors (PIs) in the lung is a critical determinant for a number of chronic inflammatory lung diseases such as chronic obstructive pulmonary disease, cystic fibrosis and acute lung injury. During activation at inflammatory sites,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Glycobiology
Hauptverfasser: Craciun, Ioana, Fenner, Amanda M, Kerns, Robert J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976519/
https://ncbi.nlm.nih.gov/pubmed/26850997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cww011
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