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Hepatic Hemorrhage as a Consequence of Rapid Response to Combined Targeted Therapy in Metastatic Melanoma

A middle-aged female with metastatic melanoma was found to have hemoperitoneum after starting systemic therapy with the BRAF and MEK inhibitors dabrafenib and trametinib. Etiology proved to be bleeding from a known hepatic metastasis. The patient was managed conservatively and eventually resumed sys...

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Detalhes bibliográficos
Publicado no:J Surg Oncol
Main Authors: FLAHERTY, DEVIN C., HOFFNER, BRIANNA W., LAU, BRIANA J., HAMID, OMID, FARIES, MARK B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976480/
https://ncbi.nlm.nih.gov/pubmed/26503563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jso.24078
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