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Driving change: kidney proximal tubule CSF-1 polarizes macrophages

Macrophage colony-stimulating factor (CSF-1 or M-CSF) is important for kidney repair after acute kidney injury (AKI). CSF-1 is upregulated in tubule epithelial cells in response to kidney injury stimuli and binds to its sole receptor, CSF1R, in an autocrine and paracrine manner. Wang and colleagues...

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Publicado en:Kidney Int
Autores principales: Perry, Heather M., Okusa, Mark D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976441/
https://ncbi.nlm.nih.gov/pubmed/26649657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.324
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