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Retinoic acid receptors initiate induction of the cytomegalovirus enhancer in embryonal cells.

Reactivation of latent virus is believed to result from a signal transduction event that induces immediate-early (IE) gene transcription. Evidence is presented that the major IE promoter (MIEP) of human cytomegalovirus (hCMV) is activated by physiological levels of retinoic acid (RA) in human embryo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ghazal, P, DeMattei, C, Giulietti, E, Kliewer, S A, Umesono, K, Evans, R M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49764/
https://ncbi.nlm.nih.gov/pubmed/1323848
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