Retinoic acid receptors initiate induction of the cytomegalovirus enhancer in embryonal cells.

Reactivation of latent virus is believed to result from a signal transduction event that induces immediate-early (IE) gene transcription. Evidence is presented that the major IE promoter (MIEP) of human cytomegalovirus (hCMV) is activated by physiological levels of retinoic acid (RA) in human embryo...

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Autori principali: Ghazal, P, DeMattei, C, Giulietti, E, Kliewer, S A, Umesono, K, Evans, R M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC49764/
https://ncbi.nlm.nih.gov/pubmed/1323848
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