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Preventive effect of sildenafil on right ventricular function in rats with monocrotaline-induced pulmonary arterial hypertension

The present study aimed to evaluate the preventive effect of sildenafil treatment on pulmonary hypertension (PH) induced by monocrotaline (MCT) in rats. Fifty-four 12-week-old male Sprague–Dawley rats were injected with MCT or saline solution (MCT-injected rats: n=36; saline: n=18). Serial echocardi...

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Bibliografiske detaljer
Udgivet i:Exp Anim
Main Authors: Yoshiyuki, Rieko, Tanaka, Ryo, Fukushima, Ryuji, Machida, Noboru
Format: Artigo
Sprog:Inglês
Udgivet: Japanese Association for Laboratory Animal Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976235/
https://ncbi.nlm.nih.gov/pubmed/26876436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.15-0070
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