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Comparison of preventive effect of sildenafil and therapeutic effect of sildenafil treatment in rats with monocrotaline-induced pulmonary arterial hypertension

This study aimed to investigate the potential effects of sildenafil on pulmonary hypertension (PH) in the monocrotaline (MCT)-induced PH rat. Twenty-four, 12-week-old, male Sprague-Dawley rats were injected with MCT or saline solution. After injection of MCT, rats received oral sildenafil immediatel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Vet Med Sci
Hauptverfasser: YOSHIYUKI, Rieko, FUKUSHIMA, Ryuji, TANAKA, Ryo, MACHIDA, Noboru
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Japanese Society of Veterinary Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095631/
https://ncbi.nlm.nih.gov/pubmed/27320637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.15-0544
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