Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila

Stem cells are regulated both intrinsically and externally, including by signals from the local environment and distant organs. To identify genes and pathways that regulate stem-cell fates in the whole organism, we perform a genome-wide transgenic RNAi screen through ubiquitous gene knockdowns, focu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Ying, Ge, Qinglan, Chan, Brian, Liu, Hanhan, Singh, Shree Ram, Manley, Jacob, Lee, Jae, Weideman, Ann Marie, Hou, Gerald, Hou, Steven X.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976209/
https://ncbi.nlm.nih.gov/pubmed/27484291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12149
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