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Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro

Most sub-cellular cargos are transported along microtubules by kinesin and dynein molecular motors, but how transport is regulated is not well understood. It is unknown whether local control is possible, for example, by changes in specific cargo-associated motor behaviour to react to impediments. He...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Reddy, Babu J. N., Mattson, Michelle, Wynne, Caitlin L., Vadpey, Omid, Durra, Abdo, Chapman, Dail, Vallee, Richard B., Gross, Steven P.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976208/
https://ncbi.nlm.nih.gov/pubmed/27489054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12259
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