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Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis
Lis1, Nudel/NudE, and dynactin are regulators of cytoplasmic dynein, a minus end–directed, microtubule (MT)-based motor required for proper spindle assembly and orientation. In vitro studies have shown that dynactin promotes processive movement of dynein on MTs, whereas Lis1 causes dynein to enter a...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826990/ https://ncbi.nlm.nih.gov/pubmed/24025714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-05-0283 |
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