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ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes

Histone acetylation, including acetylated H3K14 (H3K14ac), is generally linked to gene activation. Monomethylated histone H3 lysine 4 (H3K4me1), together with other gene-activating marks, denotes active genes. In contrast to usual gene-activating can function of H3K14ac and H3K4me1, we here show tha...

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Publicado en:Mol Cell
Main Authors: Li, Na, Li, Yuanyuan, Lv, Jie, Zheng, Xiangdong, Wen, Hong, Shen, Hongjie, Zhu, Guangjing, Chen, Tsai-Yu, Dhar, Shilpa S., Kan, Pu-Yeh, Wang, Zhibin, Shiekhattar, Ramin, Shi, Xiaobing, Lan, Fei, Chen, Kaifu, Li, Wei, Li, Haitao, Lee, Min Gyu
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975651/
https://ncbi.nlm.nih.gov/pubmed/27477906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.06.035
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