Modified AS1411 Aptamer Suppresses Hepatocellular Carcinoma by Up-Regulating Galectin-14

Aptamers are small synthetic oligonucleotides that bind to target proteins with high specificity and affinity. AS1411 is an aptamer that binds to nucleolin, which is overexpressed in the cytoplasm and occurs on the surface of cancer cells. We investigated the therapeutic potential of aptamers in hep...

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Bibliographic Details
Published in:PLoS One
Main Authors: Cho, Yuri, Lee, Yun Bin, Lee, Jeong-Hoon, Lee, Dong Hyeon, Cho, Eun Ju, Yu, Su Jong, Kim, Yoon Jun, Kim, Jong In, Im, Jong Hun, Lee, Jung Hwan, Oh, Eun Ju, Yoon, Jung-Hwan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975508/
https://ncbi.nlm.nih.gov/pubmed/27494117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160822
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