Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120 catenin activity

E-cadherin and p120 catenin (p120) are essential for epithelial homeostasis, but can also exert pro-tumorigenic activities. Here, we resolve this apparent paradox by identifying two spatially and functionally distinct junctional complexes in non-transformed polarized epithelial cells: one growth sup...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Kourtidis, Antonis, Ngok, Siu P., Pulimeno, Pamela, Feathers, Ryan W., Carpio, Lomeli R., Baker, Tiffany R., Carr, Jennifer M., Yan, Irene K., Borges, Sahra, Perez, Edith A., Storz, Peter, Copland, John A., Patel, Tushar, Thompson, E. Aubrey, Citi, Sandra, Anastasiadis, Panos Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975377/
https://ncbi.nlm.nih.gov/pubmed/26302406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3227
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