Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells

c-Kit, a receptor tyrosine kinase, is involved in intracellular signaling, and the mutated form of c-Kit plays a crucial role in occurrence of some cancers. The function of c-Kit has led to the concept that inhibiting c-Kit kinase activity can be a target for cancer therapy. The promising results of...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Abbaspour Babaei, Maryam, Kamalidehghan, Behnam, Saleem, Mohammad, Huri, Hasniza Zaman, Ahmadipour, Fatemeh
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975146/
https://ncbi.nlm.nih.gov/pubmed/27536065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S89114
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