Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells

c-Kit, a receptor tyrosine kinase, is involved in intracellular signaling, and the mutated form of c-Kit plays a crucial role in occurrence of some cancers. The function of c-Kit has led to the concept that inhibiting c-Kit kinase activity can be a target for cancer therapy. The promising results of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Abbaspour Babaei, Maryam, Kamalidehghan, Behnam, Saleem, Mohammad, Huri, Hasniza Zaman, Ahmadipour, Fatemeh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975146/
https://ncbi.nlm.nih.gov/pubmed/27536065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S89114
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