S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells

BACKGROUND: The S6 Kinase (S6K) proteins are some of the main downstream effectors of the mammalian Target Of Rapamycin (mTOR) and act as key regulators of protein synthesis and cell growth. S6K is overexpressed in a variety of human tumors and is correlated to poor prognosis in prostate cancer. Due...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Cancer
Prif Awduron: Amaral, Camila L., Freitas, Lidia B., Tamura, Rodrigo E., Tavares, Mariana R., Pavan, Isadora C. B., Bajgelman, Marcio C., Simabuco, Fernando M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974797/
https://ncbi.nlm.nih.gov/pubmed/27491285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2629-y
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