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S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells
BACKGROUND: The S6 Kinase (S6K) proteins are some of the main downstream effectors of the mammalian Target Of Rapamycin (mTOR) and act as key regulators of protein synthesis and cell growth. S6K is overexpressed in a variety of human tumors and is correlated to poor prognosis in prostate cancer. Due...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974797/ https://ncbi.nlm.nih.gov/pubmed/27491285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2629-y |
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