A radiosensitizing effect of RAD51 inhibition in glioblastoma stem-like cells

BACKGROUND: Radioresistant glioblastoma stem cells (GSCs) contribute to tumor recurrence and identification of the molecular targets involved in radioresistance mechanisms is likely to enhance therapeutic efficacy. This study analyzed the DNA damage response following ionizing radiation (IR) in 10 G...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Balbous, Anaïs, Cortes, Ulrich, Guilloteau, Karline, Rivet, Pierre, Pinel, Baptiste, Duchesne, Mathilde, Godet, Julie, Boissonnade, Odile, Wager, Michel, Bensadoun, René Jean, Chomel, Jean-Claude, Karayan-Tapon, Lucie
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974671/
https://ncbi.nlm.nih.gov/pubmed/27495836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2647-9
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