H/KDEL receptors mediate host cell intoxication by a viral A/B toxin in yeast

A/B toxins such as cholera toxin, Pseudomonas exotoxin and killer toxin K28 contain a KDEL-like amino acid motif at one of their subunits which ensures retrograde toxin transport through the secretory pathway of a target cell. As key step in host cell invasion, each toxin binds to distinct plasma me...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Becker, Björn, Blum, Andrea, Gießelmann, Esther, Dausend, Julia, Rammo, Domenik, Müller, Nina C., Tschacksch, Emilia, Steimer, Miriam, Spindler, Jenny, Becherer, Ute, Rettig, Jens, Breinig, Frank, Schmitt, Manfred J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974620/
https://ncbi.nlm.nih.gov/pubmed/27493088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31105
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