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High glucose-induced cytoplasmic translocation of Dnmt3a contributes to CTGF hypo-methylation in mesangial cells

Connective tissue growth factor (CTGF) plays an essential role in the pathogenesis of diabetic nephropathy and we have previously identified that high glucose induced the expression of CTGF by decreasing DNA methylation. The aim of the present study was to investigate the underlying mechanisms of th...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Zhang, Hao, Li, Aimei, Zhang, Wei, Huang, Zhijun, Wang, Jianwen, Yi, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974599/
https://ncbi.nlm.nih.gov/pubmed/27364355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160141
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