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Cancer-associated fibroblasts in hepatocellular carcinoma

The hepatic stellate cells in the liver are stimulated sustainably by chronic injury of the hepatocytes, activating myofibroblasts, which produce abundant collagen. Myofibroblasts are the major source of extracellular proteins during fibrogenesis, and may directly, or secreted products, contribute t...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Kubo, Norio, Araki, Kenichiro, Kuwano, Hiroyuki, Shirabe, Ken
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974583/
https://ncbi.nlm.nih.gov/pubmed/27570421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i30.6841
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