Conditional Deletion of Smad1 Ameliorates Glomerular Injury in Progressive Glomerulonephritis

Matrix expansion and cell proliferation are concomitantly observed in various glomerular injuries. However, the molecular mechanisms responsible for these changes have not been fully elucidated. We have reported that Smad1 is a key signalling molecule that regulates the transcription of type IV coll...

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Publicat a:Sci Rep
Autors principals: Araki, Makoto, Matsubara, Takeshi, Abe, Hideharu, Torikoshi, Kazuo, Mima, Akira, Iehara, Noriyuki, Fukatsu, Atsushi, Kita, Toru, Arai, Hidenori, Doi, Toshio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974558/
https://ncbi.nlm.nih.gov/pubmed/27492138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31216
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