Conditional Deletion of Smad1 Ameliorates Glomerular Injury in Progressive Glomerulonephritis

Matrix expansion and cell proliferation are concomitantly observed in various glomerular injuries. However, the molecular mechanisms responsible for these changes have not been fully elucidated. We have reported that Smad1 is a key signalling molecule that regulates the transcription of type IV coll...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Araki, Makoto, Matsubara, Takeshi, Abe, Hideharu, Torikoshi, Kazuo, Mima, Akira, Iehara, Noriyuki, Fukatsu, Atsushi, Kita, Toru, Arai, Hidenori, Doi, Toshio
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974558/
https://ncbi.nlm.nih.gov/pubmed/27492138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31216
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