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Conditional Deletion of Smad1 Ameliorates Glomerular Injury in Progressive Glomerulonephritis

Matrix expansion and cell proliferation are concomitantly observed in various glomerular injuries. However, the molecular mechanisms responsible for these changes have not been fully elucidated. We have reported that Smad1 is a key signalling molecule that regulates the transcription of type IV coll...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Araki, Makoto, Matsubara, Takeshi, Abe, Hideharu, Torikoshi, Kazuo, Mima, Akira, Iehara, Noriyuki, Fukatsu, Atsushi, Kita, Toru, Arai, Hidenori, Doi, Toshio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974558/
https://ncbi.nlm.nih.gov/pubmed/27492138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31216
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