Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein

EBV is the major infectious environmental risk factor for multiple sclerosis (MS), but the underlying mechanisms remain obscure. Patient studies do not allow manipulation in vivo. We used the experimental autoimmune encephalomyelitis (EAE) models in the common marmoset and rhesus monkey to model the...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Jagessar, S. Anwar, Holtman, Inge R., Hofman, Sam, Morandi, Elena, Heijmans, Nicole, Laman, Jon D., Gran, Bruno, Faber, Bart W., van Kasteren, Sander I., Eggen, Bart J. L., ‘t Hart, Bert A.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
Assuntos:
Autoimmunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974490/
https://ncbi.nlm.nih.gov/pubmed/27412414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600124
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