Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters

The MuvB complex recruits transcription factors to activate or repress genes with cell cycle-dependent expression patterns. MuvB contains the DNA-binding protein LIN54, which directs the complex to promoter cell cycle genes homology region (CHR) elements. Here we characterize the DNA-binding propert...

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Pubblicato in:Nat Commun
Autori principali: Marceau, Aimee H., Felthousen, Jessica G., Goetsch, Paul D., Iness, Audra N., Lee, Hsiau-Wei, Tripathi, Sarvind M., Strome, Susan, Litovchick, Larisa, Rubin, Seth M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974476/
https://ncbi.nlm.nih.gov/pubmed/27465258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12301
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