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Constitutive Endocytosis of VEGFR2 Protects the Receptor against Shedding
VEGFR2 plays a fundamental role in blood vessel formation and in life threatening diseases, such as cancer angiogenesis and cardiovascular disorders. Although inactive growth factor receptors are mainly localized at the plasma membrane, VEGFR2 undergoes constitutive endocytosis (in the absence of li...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974401/ https://ncbi.nlm.nih.gov/pubmed/27298320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.730309 |
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