E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment

BACKGROUND: Refractory surface of wound and dermal chronic ulcer are largely attributed to poor neovascularization. We have previously shown that E2F1 suppresses VEGF expression in the ischemic heart, and that genetic deletion of E2F1 leads to better cardiac recovery. However, whether E2F1 has a rol...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Wang, Ningning, Wu, Yiping, Zeng, Ning, Wang, Haiping, Deng, Pei, Xu, Yi, Feng, Youping, Zeng, Hong, Yang, Hongxia, Hou, Kai, Wang, Andrew, Parthasarathy, Keshav, Goyal, Samaksh, Qin, Gangjian, Wu, Min
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973919/
https://ncbi.nlm.nih.gov/pubmed/27490344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160411
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