Effects of a Soluble Epoxide Hydrolase Inhibitor on Lipopolysaccharide-Induced Acute Lung Injury in Mice

OBJECTIVES: Inflammation plays a key role in the pathogenesis of acute lung injury (ALI). Soluble epoxide hydrolase (sEH) is suggested as a vital pharmacologic target for inflammation. In this study, we determined whether a sEH inhibitor, AUDA, exerts lung protection in lipopolysaccharide (LPS)-indu...

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Bibliographic Details
Published in:PLoS One
Main Authors: Tao, Wei, Li, Ping-Song, Yang, Liu-Qing, Ma, Yong-Bo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973880/
https://ncbi.nlm.nih.gov/pubmed/27490848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160359
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