CD4(+)CD25(hi)Foxp3(+) Cells Exacerbate Bleomycin-Induced Pulmonary Fibrosis

Idiopathic pulmonary fibrosis is a fatal lung disease with a median survival of 2 to 5 years. A decade of studies has downplayed inflammation contributing to its pathogenesis. However, these studies preceded the discovery of regulatory T cells (Tregs) and all of their functions. On the basis of huma...

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Bibliografiske detaljer
Udgivet i:Am J Pathol
Main Authors: Birjandi, Shirin Z., Palchevskiy, Vyacheslav, Xue, Ying Ying, Nunez, Stefanie, Kern, Rita, Weigt, S. Sam, Lynch, Joseph P., Chatila, Talal A., Belperio, John A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2016
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973661/
https://ncbi.nlm.nih.gov/pubmed/27317904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.03.020
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